Balancing gene drive spread and fitness cost

Gene drives are any natural or artificial mechanism of spreading a genetic ‘cargo’ into a target population. Gene drives are introduced by the release of genetically modified (transgenic) organisms carrying the cargo gene. These genes almost always inflict a fitness cost on transgenic organisms, underlying a balance between the spread of the gene drive and the cost it imposes.

Modeling the opioid epidemic

A collaborative project with the goal of mathematically modeling the opioid epidemic at the state level and using the results to inform directions of control.